Technology Description

The World’s First Non-invasive absolute intracranial pressure value meter:

  • Based on two depth Doppler ultrasound technology;                                                                                                   
  • Without the need for calibration to the individual patient;
  • Reliable:

       – Designed to be simple and rapid to use with minimal training;
       – The ability to measure the ICP separately in left and right hemispheres of the brain;
       – 0-50 mmHg measurement range;
       – Automatic measurements, rapid results in few minutes.

  • Accurate and precise:

       – Clinically validated.

  • Safe:

       – Power levels matching approved ultrasound devices;
       – Avoids the complications of invasive ICP monitoring;
       – Disposable pressure cuff and head frame;
       – Maximum pressure levels on orbit equivalent to 70 cm depth of water.

  • Intellectual property protected by the US, EU and Japan patents;
  • R&D and D&D funded by the US Dept. of Defence, Dept. of the Army, European Commission FP7 projects and Vittamed LTD

The Vittamed two-depth Doppler ultrasound technology is the first non-invasive ICP meter capable of accurately, precisely and reliably measuring the absolute value of intracranial pressure (ICP) without the need for periodic calibration to the individual patient.

Vittamed non-invasive aICP measurement technology solves the main limiting problem of all other technologies designed to measure ICP - the individual patient calibration problem. The only solution is to eliminate need of calibration by direct comparison of aICP and externaly applied pressure – same fundamental principle used to measure blood pressure with a sphygmomanometer.

A sphygmomanometer works using a balance principle; an air-filled pressure cuff wrapped around the arm compresses the brachial artery to a point where blood can no longer flow. The examiner slowly releases the air from the cuff and uses a stethoscope to listen for the return of blood flow. At the balance point, where pressure in the cuff equals systolic artery pressure, a ‘whooshing’ noise can be heard as blood flows through the artery again.

We use Doppler ultrasound to translate this principle to the measurement of intracranial pressure. As with a sphygmomanometer, a pressure cuff is used - in this case to compress the tissues surrounding the eye and change the characteristics of blood flowing from inside the skull cavity into the eye socket.

The eye artery (ophthalmic artery) is a unique vessel with intracranial and extracranial segments - natural scales for absolute ICP measurement.

In place of the stethoscope, a Doppler ultrasound beam measures the blood flow in intracranial and extracranial segments of the ophthalmic artery. The point where the pulsatility in the two sections is equal is the point at which the applied external pressure equals the intracranial pressure.


Clinical Evidence